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🧬 Transposable DNA elements are highly repetitive sequences that make up ~1/2 of the human genome. New in Nature Communications, JAX's Beck lab studies their role in generating human DNA variation through transposable element-mediated rearrangements (TEMRs). TEMRs are enriched in genes and can create potentially important risk alleles such as a deletion in TRIM65, a known #cancer biomarker and therapeutic target. #jaxresearch | The Jackson Laboratory
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🧬 Transposable DNA elements are highly repetitive sequences that make up ~1/2 of the human genome. New in Nature Communications, JAX's Beck lab studies their role in generating human DNA variation through transposable element-mediated rearrangements (TEMRs). TEMRs are enriched in genes and can create potentially important risk alleles such as a deletion in TRIM65, a known #cancer biomarker and therapeutic target. #jaxresearch | The Jackson Laboratory
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Not all of your DNA just sits there. Some of it can move.. and it has changed evolution! Transposable elements sound chaotic, but they’re a huge part of how genomes actually work 🧬 Head to my profile for part 2.. how this leads to the placenta. _____ Citations: Ayarpadikannan, S., & Kim, H.-S. (2014). The impact of transposable elements in genome evolution and genetic instability and their implications in various diseases. Genomics & Informatics, 12(3), 98–104. https://www.ncbi.nlm.nih.gov/pmc/
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